242 search results - page 44 / 49 » Evolutionary sequence analysis of complete eukaryote genomes |
ICSE
1997
IEEE-ACM
15 years 1 months ago
1997
IEEE-ACM
Software architectures evolve as the result of numerous, interrelated design decisions. At any point in an architecture’s evolution, current decisions can critically affect alte...
BMCBI
2007
14 years 9 months ago
2007
Background: Evolutionary conservation has been used successfully to help identify cis-acting DNA regions that are important in regulating tissue-specific gene expression. Motivate...
105
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GCB
2004
Springer
15 years 1 months ago
2004
Springer
: In biological sequence analysis, position specific scoring matrices (PSSMs) are widely used to represent sequence motifs. In this paper, we present a new nonheuristic algorithm, ...
BMCBI
2010
14 years 9 months ago
2010
Background: The estimation of demographic parameters from genetic data often requires the computation of likelihoods. However, the likelihood function is computationally intractab...
112
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BMCBI
2011
14 years 4 months ago
2011
Background: The prediction of the structure of large RNAs remains a particular challenge in bioinformatics, due to the computational complexity and low levels of accuracy of state...