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» Evolutionary sequence analysis of complete eukaryote genomes
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NAR
2008
91views more  NAR 2008»
14 years 9 months ago
GenBank
GenBank (R) is a comprehensive sequence database that contains publicly available DNA sequences for more than 119 000 different organisms, obtained primarily through the submissio...
Dennis A. Benson, Ilene Karsch-Mizrachi, David J. ...
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BMCBI
2006
111views more  BMCBI 2006»
14 years 9 months ago
Development of an unbiased statistical method for the analysis of unigenic evolution
Background: Unigenic evolution is a powerful genetic strategy involving random mutagenesis of a single gene product to delineate functionally important domains of a protein. This ...
Colleen D. Behrsin, Chris J. Brandl, David W. Litc...
CLADE
2008
IEEE
15 years 4 months ago
SWARM: a scientific workflow for supporting bayesian approaches to improve metabolic models
With the exponential growth of complete genome sequences, the analysis of these sequences is becoming a powerful approach to build genome-scale metabolic models. These models can ...
Xinghua Shi, Rick Stevens
BMCBI
2005
223views more  BMCBI 2005»
14 years 9 months ago
Bioinformatics approaches for cross-species liver cancer analysis based on microarray gene expression profiling
Background: The completion of the sequencing of human, mouse and rat genomes and knowledge of cross-species gene homologies enables studies of differential gene expression in anim...
Hong Fang, Weida Tong, Roger Perkins, Leming M. Sh...
BMCBI
2004
133views more  BMCBI 2004»
14 years 9 months ago
Evaluation of several lightweight stochastic context-free grammars for RNA secondary structure prediction
Background: RNA secondary structure prediction methods based on probabilistic modeling can be developed using stochastic context-free grammars (SCFGs). Such methods can readily co...
Robin D. Dowell, Sean R. Eddy