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140
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CORR
2008
Springer
156views Education» more  CORR 2008»
15 years 3 months ago
Artificial Immune Systems (AIS) - A New Paradigm for Heuristic Decision Making
Over the last few years, more and more heuristic decision making techniques have been inspired by nature, e.g. evolutionary algorithms, ant colony optimisation and simulated annea...
Uwe Aickelin
155
Voted
BMCBI
2006
102views more  BMCBI 2006»
15 years 3 months ago
Protein secondary structure prediction for a single-sequence using hidden semi-Markov models
Background: The accuracy of protein secondary structure prediction has been improving steadily towards the 88% estimated theoretical limit. There are two types of prediction algor...
Zafer Aydin, Yucel Altunbasak, Mark Borodovsky
230
Voted
BMCBI
2006
140views more  BMCBI 2006»
15 years 3 months ago
MACSIMS : multiple alignment of complete sequences information management system
Background: In the post-genomic era, systems-level studies are being performed that seek to explain complex biological systems by integrating diverse resources from fields such as...
Julie D. Thompson, Arnaud Muller, Andrew M. Waterh...
136
Voted
BMCBI
2006
130views more  BMCBI 2006»
15 years 3 months ago
Docking protein domains in contact space
Background: Many biological processes involve the physical interaction between protein domains. Understanding these functional associations requires knowledge of the molecular str...
Stefano Lise, Alice Walker-Taylor, David T. Jones
133
Voted
BMCBI
2006
116views more  BMCBI 2006»
15 years 3 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...