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» Evolving Better Multiple Sequence Alignments
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RECOMB
1997
Springer
15 years 1 months ago
A more efficient approximation scheme for tree alignment
We present a new polynomial time approximation scheme (PTAS) for tree alignment, which is an important variant of multiple sequence alignment. As in the existing PTASs in the liter...
Lusheng Wang, Tao Jiang, Dan Gusfield
91
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BMCBI
2010
104views more  BMCBI 2010»
14 years 9 months ago
Parameters for accurate genome alignment
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Martin C. Frith, Michiaki Hamada, Paul Horton
BMCBI
2006
96views more  BMCBI 2006»
14 years 9 months ago
Structure alignment based on coding of local geometric measures
Background: A structure alignment method based on a local geometric property is presented and its performance is tested in pairwise and multiple structure alignments. In this appr...
Peter L. Chang, Andrew W. Rinne, T. Gregory Dewey
RECOMB
2003
Springer
15 years 10 months ago
Accurate detection of very sparse sequence motifs
Protein sequence alignments are more reliable the shorter the evolutionary distance. Here, we align distantly related proteins using many closely spaced intermediate sequences as ...
Andreas Heger, Michael Lappe, Liisa Holm
BMCBI
2004
94views more  BMCBI 2004»
14 years 9 months ago
GASP: Gapped Ancestral Sequence Prediction for proteins
Background: The prediction of ancestral protein sequences from multiple sequence alignments is useful for many bioinformatics analyses. Predicting ancestral sequences is not a sim...
Richard J. Edwards, Denis C. Shields