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GECCO
2003
Springer
128views Optimization» more  GECCO 2003»
15 years 4 months ago
Evolving Consensus Sequence for Multiple Sequence Alignment with a Genetic Algorithm
In this paper we present an approach that evolves the consensus sequence [25] for multiple sequence alignment (MSA) with genetic algorithm (GA). We have developed an encoding schem...
Conrad Shyu, James A. Foster
GECCO
2004
Springer
137views Optimization» more  GECCO 2004»
15 years 5 months ago
Evolving Better Multiple Sequence Alignments
Aligning multiple DNA or protein sequences is a fundamental step in the analyses of phylogeny, homology and molecular structure. Heuristic algorithms are applied because optimal mu...
Luke Sheneman, James A. Foster
122
Voted
BIOCOMP
2006
15 years 1 months ago
PAC: Progressive Alignment with Consensus Sequences
Computation of multiple sequence alignments is one of the major open problems in computational molecular biology. The purpose of this study was to provide a new method, PAC (Progre...
Ke Liu, Mansur H. Samadzadeh
GECCO
2006
Springer
171views Optimization» more  GECCO 2006»
15 years 3 months ago
A hybrid genetic search for multiple sequence alignment
This paper proposes a hybrid genetic algorithm for multiple sequence alignment. The algorithm evolves guide sequences and aligns input sequences based on the guide sequences. It a...
Seung-Hyun Moon, Sung-Soon Choi, Byung Ro Moon
74
Voted
GECCO
2008
Springer
165views Optimization» more  GECCO 2008»
15 years 22 days ago
Multiple sequence alignment using a GLOCSA guided genetic algorithm
This paper introduces GLOCSA as a new scoring function to rate multiple sequence alignments. It is intended to be simple, considering the whole alignment at once and reflecting t...
Edgar David Arenas-Díaz, Helga Ochoterena-B...