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» Evolving fuzzy rules to model gene expression
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BCB
2010
127views Bioinformatics» more  BCB 2010»
14 years 6 months ago
A novel network model for molecular prognosis
Network-based genome-wide association studies (NWAS) utilize the molecular interactions between genes and functional pathways in biomarker identification. This study presents a no...
Ying-Wooi Wan, Swetha Bose, James Denvir, Nancy La...
BIOSYSTEMS
2007
175views more  BIOSYSTEMS 2007»
14 years 12 months ago
Alternative routes and mutational robustness in complex regulatory networks
Alternative pathways through a gene regulation network connect a regulatory molecule to its (indirect) regulatory target via different intermediate regulators. We here show for tw...
Andreas Wagner, Jeremiah Wright
104
Voted
BMCBI
2005
141views more  BMCBI 2005»
14 years 11 months ago
Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis
Background: Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regenerati...
Nils E. Magnusson, Alessandra K. Cardozo, Mogens K...
GECCO
1999
Springer
130views Optimization» more  GECCO 1999»
15 years 4 months ago
Heterochrony and Adaptation in Developing Neural Networks
This paper discusses the simulation results of a model of biological development for neural networks based on a regulatory genome. The model’s results are analyzed using the fra...
Angelo Cangelosi
BMCBI
2007
111views more  BMCBI 2007»
14 years 11 months ago
CATMA, a comprehensive genome-scale resource for silencing and transcript profiling of Arabidopsis genes
Background: The Complete Arabidopsis Transcript MicroArray (CATMA) initiative combines the efforts of laboratories in eight European countries [1] to deliver gene-specific sequenc...
Gert Sclep, Joke Allemeersch, Robin Liechti, Bj&ou...