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» Evolving genetic regulatory networks for systems biology
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BMCBI
2008
146views more  BMCBI 2008»
14 years 9 months ago
Rank-based edge reconstruction for scale-free genetic regulatory networks
Background: The reconstruction of genetic regulatory networks from microarray gene expression data has been a challenging task in bioinformatics. Various approaches to this proble...
Guanrao Chen, Peter Larsen, Eyad Almasri, Yang Dai
BERTINORO
2005
Springer
15 years 3 months ago
Evolving Fractal Gene Regulatory Networks for Graceful Degradation of Software
Fractal proteins are an evolvable method of mapping genotype to phenotype through a developmental process, where genes are expressed into proteins comprised of subsets of the Mande...
Peter J. Bentley
BIB
2008
93views more  BIB 2008»
14 years 9 months ago
A structured approach for the engineering of biochemical network models, illustrated for signalling pathways
Quantitative models of biochemical networks (signal transduction cascades, metabolic pathways, gene regulatory circuits) are a central component of modern systems biology. Buildin...
Rainer Breitling, David Gilbert, Monika Heiner, Ri...
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ICANN
2007
Springer
15 years 3 months ago
Identifying Binding Sites in Sequential Genomic Data
The identification of cis-regulatory binding sites in DNA is a difficult problem in computational biology. To obtain a full understanding of the complex machinery embodied in genet...
Mark Robinson, Cristina González Castellano...
SAGA
2005
Springer
15 years 3 months ago
Self-replication, Evolvability and Asynchronicity in Stochastic Worlds
We consider temporal aspects of self-replication and evolvability – in particular, the massively asynchronous parallel and distributed nature of living systems. Formal views of s...
Chrystopher L. Nehaniv