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» Evolving genetic regulatory networks for systems biology
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HYBRID
2007
Springer
15 years 3 months ago
Switch Detection in Genetic Regulatory Networks
Abstract. This paper considers piecewise affine models of genetic regulatory networks and focuses on the problem of detecting switches among different modes of operation in gene e...
Riccardo Porreca, Giancarlo Ferrari-Trecate, Danie...
ECAI
2008
Springer
14 years 11 months ago
Temporal Logic Patterns for Querying Qualitative Models of Genetic Regulatory Networks
Formal verification based on model checking provides a powerful technology to query qualitative models of dynamical systems. The application of model-checking approaches is hamper...
Pedro T. Monteiro, Delphine Ropers, Radu Mateescu,...
BMCBI
2008
202views more  BMCBI 2008»
14 years 9 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
74
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GECCO
2005
Springer
127views Optimization» more  GECCO 2005»
15 years 3 months ago
Identifying valid solutions for the inference of regulatory networks
In this paper, we address the problem of finding gene regulatory networks from experimental DNA microarray data. The problem often is multi-modal and therefore appropriate optimi...
Christian Spieth, Felix Streichert, Nora Speer, An...
TACAS
2007
Springer
92views Algorithms» more  TACAS 2007»
15 years 3 months ago
Model Checking Liveness Properties of Genetic Regulatory Networks
Abstract. Recent studies have demonstrated the possibility to build genetic regulatory networks that confer a desired behavior to a living organism. However, the design of these ne...
Grégory Batt, Calin Belta, Ron Weiss