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» Evolving genetic regulatory networks for systems biology
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APIN
1998
139views more  APIN 1998»
14 years 9 months ago
Evolutionary Learning of Modular Neural Networks with Genetic Programming
Evolutionary design of neural networks has shown a great potential as a powerful optimization tool. However, most evolutionary neural networks have not taken advantage of the fact ...
Sung-Bae Cho, Katsunori Shimohara
ASC
2007
14 years 9 months ago
Evolving an artificial neural network classifier for condition monitoring of rotating mechanical systems
We present the results of our investigation into the use of Genetic Algorithms (GAs) for identifying near optimal design parameters of diagnostic systems that are based on Artifici...
Abhinav Saxena, Ashraf Saad
BMCBI
2007
130views more  BMCBI 2007»
14 years 9 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
BIOCOMP
2010
14 years 7 months ago
A Model Reduction Technique for Stochastic Biochemical Kinetics
Abstract-- Modeling the intermolecular reactions in a single cell is a critical problem in computational biology. Biochemical reaction systems often involve species in both low and...
Silvana Ilie, Ekaterina Kudashkina
GECCO
2004
Springer
132views Optimization» more  GECCO 2004»
15 years 3 months ago
Optimizing Topology and Parameters of Gene Regulatory Network Models from Time-Series Experiments
Abstract. In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. Different approaches to infer the dependencies of gene r...
Christian Spieth, Felix Streichert, Nora Speer, An...