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» Evolving genetic regulatory networks for systems biology
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88
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GECCO
2007
Springer
140views Optimization» more  GECCO 2007»
15 years 3 months ago
Program evolvability under environmental variations and neutrality
Biological organisms employ various mechanisms to cope with the dynamic environments they live in. One recent research reported that depending on the rates of environmental variati...
Tina Yu
87
Voted
HYBRID
2001
Springer
15 years 2 months ago
Hybrid Modeling and Simulation of Biomolecular Networks
Abstract. In a biological cell, cellular functions and the genetic regulatory apparatus are implemented and controlled by a network of chemical reactions in which regulatory protei...
Rajeev Alur, Calin Belta, Franjo Ivancic
IJCAI
2001
14 years 11 months ago
Qualitative Simulation of Genetic Regulatory Networks: Method and Application
Computer modeling and simulation are indispensable for understanding the functioning of an organism on a molecular level. We present an implemented method for the qualitative simu...
Hidde de Jong, Michel Page, Céline Hernande...
90
Voted
GECCO
2005
Springer
149views Optimization» more  GECCO 2005»
15 years 3 months ago
There's more to a model than code: understanding and formalizing in silico modeling experience
Mapping biology into computation has both a domain specific aspect – biological theory – and a methodological aspect – model development. Computational modelers have implici...
Janet Wiles, Nicholas Geard, James Watson, Kai Wil...
88
Voted
RECOMB
2005
Springer
15 years 10 months ago
Combinatorial Genetic Regulatory Network Analysis Tools for High Throughput Transcriptomic Data
: A series of genome-scale algorithms and high-performance implementations is described and shown to be useful in the genetic analysis of gene transcription. With them it is possib...
Elissa J. Chesler, Michael A. Langston