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BMCBI
2010
227views more  BMCBI 2010»
14 years 12 months ago
Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
Majid Masso, Iosif I. Vaisman
BMCBI
2007
168views more  BMCBI 2007»
14 years 12 months ago
Benchmarking consensus model quality assessment for protein fold recognition
Background: Selecting the highest quality 3D model of a protein structure from a number of alternatives remains an important challenge in the field of structural bioinformatics. M...
Liam J. McGuffin
BMCBI
2008
107views more  BMCBI 2008»
14 years 12 months ago
A machine learning approach to explore the spectra intensity pattern of peptides using tandem mass spectrometry data
Background: A better understanding of the mechanisms involved in gas-phase fragmentation of peptides is essential for the development of more reliable algorithms for high-throughp...
Cong Zhou, Lucas D. Bowler, Jianfeng Feng
BMCBI
2008
134views more  BMCBI 2008»
14 years 12 months ago
Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites
Background: Utilization of alternative initiation sites for protein translation directed by non-AUG codons in mammalian mRNAs is observed with increasing frequency. Alternative in...
Jill L. Wegrzyn, Thomas M. Drudge, Faramarz Valafa...
BMCBI
2008
116views more  BMCBI 2008»
14 years 12 months ago
IgTM: An algorithm to predict transmembrane domains and topology in proteins
Background: Due to their role of receptors or transporters, membrane proteins play a key role in many important biological functions. In our work we used Grammatical Inference (GI...
Piedachu Peris, Damián López, Marcel...