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BMCBI
2007
107views more  BMCBI 2007»
15 years 6 months ago
A computational approach for detecting peptidases and their specific inhibitors at the genome level
Background: Peptidases are proteolytic enzymes responsible for fundamental cellular activities in all organisms. Apparently about 2–5% of the genes encode for peptidases, irresp...
Lisa Bartoli, Remo Calabrese, Piero Fariselli, Dam...
BMCBI
2005
135views more  BMCBI 2005»
15 years 6 months ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...
JCB
2007
144views more  JCB 2007»
15 years 6 months ago
Statistical Estimation of Statistical Mechanical Models: Helix-Coil Theory and Peptide Helicity Prediction
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
Scott C. Schmidler, Joseph E. Lucas, Terrence G. O...
QRE
2008
140views more  QRE 2008»
15 years 5 months ago
Discrete mixtures of kernels for Kriging-based optimization
: Kriging-based exploration strategies often rely on a single Ordinary Kriging model which parametric covariance kernel is selected a priori or on the basis of an initial data set....
David Ginsbourger, Céline Helbert, Laurent ...
TKDE
2010
148views more  TKDE 2010»
15 years 4 months ago
False Negative Problem of Counting Bloom Filter
—Bloom filter is effective, space-efficient data structure for concisely representing a data set and supporting approximate membership queries. Traditionally, researchers often b...
Deke Guo, Yunhao Liu, Xiang-Yang Li, Panlong Yang
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