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» Extending Dependencies with Conditions
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79
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ALMOB
2008
131views more  ALMOB 2008»
14 years 10 months ago
Fast algorithms for computing sequence distances by exhaustive substring composition
The increasing throughput of sequencing raises growing needs for methods of sequence analysis and comparison on a genomic scale, notably, in connection with phylogenetic tree reco...
Alberto Apostolico, Olgert Denas
ALMOB
2007
74views more  ALMOB 2007»
14 years 10 months ago
Evaluating deterministic motif significance measures in protein databases
Background: Assessing the outcome of motif mining algorithms is an essential task, as the number of reported motifs can be very large. Significance measures play a central role in...
Pedro Gabriel Ferreira, Paulo J. Azevedo
84
Voted
ARTMED
2010
119views more  ARTMED 2010»
14 years 10 months ago
Fuzzy Arden Syntax: A fuzzy programming language for medicine
Objective: The programming language Arden Syntax has been optimised for use in clinical decision support systems. We describe an extension of this language named Fuzzy Arden Synta...
Thomas Vetterlein, Harald Mandl, Klaus-Peter Adlas...
83
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BMCBI
2010
97views more  BMCBI 2010»
14 years 10 months ago
Biomarker discovery in heterogeneous tissue samples -taking the in-silico deconfounding approach
Background: For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved. Conclusions have to rely on es...
Dirk Repsilber, Sabine Kern, Anna Telaar, Gerhard ...
91
Voted
BMCBI
2010
89views more  BMCBI 2010»
14 years 10 months ago
Spatial normalization improves the quality of genotype calling for Affymetrix SNP 6.0 arrays
Background: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique w...
High-Seng Chai, Terry M. Therneau, Kent R. Bailey,...