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BMCBI
2010
178views more  BMCBI 2010»
14 years 10 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...
BMCBI
2010
110views more  BMCBI 2010»
14 years 10 months ago
On the use of resampling tests for evaluating statistical significance of binding-site co-occurrence
Background: In eukaryotes, most DNA-binding proteins exert their action as members of large effector complexes. The presence of these complexes are revealed in high-throughput gen...
David S. Huen, Steven Russell
CORR
2008
Springer
92views Education» more  CORR 2008»
14 years 10 months ago
Accelerating Large-scale Data Exploration through Data Diffusion
Data-intensive applications often require exploratory analysis of large datasets. If analysis is performed on distributed resources, data locality can be crucial to high throughpu...
Ioan Raicu, Yong Zhao, Ian T. Foster, Alexander S....
BMCBI
2006
97views more  BMCBI 2006»
14 years 10 months ago
Goulphar: rapid access and expertise for standard two-color microarray normalization methods
Background: Raw data normalization is a critical step in microarray data analysis because it directly affects data interpretation. Most of the normalization methods currently used...
Sophie Lemoine, Florence Combes, Nicolas Servant, ...
BMCBI
2006
94views more  BMCBI 2006»
14 years 10 months ago
Genepi: a blackboard framework for genome annotation
Background: Genome annotation can be viewed as an incremental, cooperative, data-driven, knowledge-based process that involves multiple methods to predict gene locations and struc...
Stéphane Descorps-Declère, Danielle ...