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» Extensions to the Estimation Calculus
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BMCBI
2008
118views more  BMCBI 2008»
14 years 11 months ago
Virtual screening of GPCRs: An in silico chemogenomics approach
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Laurent Jacob, Brice Hoffmann, Véronique St...
CN
2008
127views more  CN 2008»
14 years 11 months ago
Decentralized detection of global threshold crossings using aggregation trees
The timely detection that a monitored variable has crossed a given threshold is a fundamental requirement for many network management applications. A challenge is the detection of ...
Fetahi Wuhib, Mads Dam, Rolf Stadler
COR
2008
116views more  COR 2008»
14 years 11 months ago
Supply disruptions with time-dependent parameters
We consider a firm that faces random demand and receives product from a single supplier who faces random supply. The supplier's availability may be affected by events such as...
Andrew M. Ross, Ying Rong, Lawrence V. Snyder
CORR
2010
Springer
177views Education» more  CORR 2010»
14 years 11 months ago
Supervised Random Walks: Predicting and Recommending Links in Social Networks
Predicting the occurrence of links is a fundamental problem in networks. In the link prediction problem we are given a snapshot of a network and would like to infer which interact...
Lars Backstrom, Jure Leskovec
BMCBI
2006
174views more  BMCBI 2006»
14 years 11 months ago
CARAT: A novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays
Background: DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterati...
Jing Huang, Wen Wei, Joyce Chen, Jane Zhang, Guoyi...