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» Extensions to the Estimation Calculus
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BMCBI
2006
137views more  BMCBI 2006»
14 years 11 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan
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BMCBI
2006
161views more  BMCBI 2006»
14 years 11 months ago
A novel approach to phylogenetic tree construction using stochastic optimization and clustering
Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
Ling Qin, Yixin Chen, Yi Pan, Ling Chen
BMCBI
2006
126views more  BMCBI 2006»
14 years 11 months ago
A Regression-based K nearest neighbor algorithm for gene function prediction from heterogeneous data
Background: As a variety of functional genomic and proteomic techniques become available, there is an increasing need for functional analysis methodologies that integrate heteroge...
Zizhen Yao, Walter L. Ruzzo
BMCBI
2006
103views more  BMCBI 2006»
14 years 11 months ago
Statistical inference of chromosomal homology based on gene colinearity and applications to Arabidopsis and rice
Background: The identification of chromosomal homology will shed light on such mysteries of genome evolution as DNA duplication, rearrangement and loss. Several approaches have be...
Xiyin Wang, Xiaoli Shi, Zhe Li, Qihui Zhu, Lei Kon...
CSDA
2006
191views more  CSDA 2006»
14 years 11 months ago
Forecasting daily time series using periodic unobserved components time series models
We explore a periodic analysis in the context of unobserved components time series models that decompose time series into components of interest such as trend, seasonal and irregu...
Siem Jan Koopman, Marius Ooms