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» Extracting Regulatory Gene Expression Networks From Pubmed
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ISMB
2004
15 years 1 months ago
Predicting gene regulation by sigma factors in Bacillus subtilis from genome-wide data
Motivation: Sigma factors regulate the expression of genes in Bacillus subtilis at the transcriptional level. First we assess the ability of currently available gene regulatory ne...
Michiel J. L. de Hoon, Yuko Makita, Seiya Imoto, K...
KDD
2004
ACM
108views Data Mining» more  KDD 2004»
16 years 3 days ago
Sleeved coclustering
A coCluster of a m?n matrix X is a submatrix determined by a subset of the rows and a subset of the columns. The problem of finding coClusters with specific properties is of inter...
Avraham A. Melkman, Eran Shaham
BMCBI
2006
239views more  BMCBI 2006»
14 years 11 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
BMCBI
2010
100views more  BMCBI 2010»
14 years 12 months ago
Trimming of mammalian transcriptional networks using network component analysis
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...
Linh M. Tran, Daniel R. Hyduke, James C. Liao
BMCBI
2004
115views more  BMCBI 2004»
14 years 11 months ago
Quantifying the relationship between co-expression, co-regulation and gene function
Background: It is thought that genes with similar patterns of mRNA expression and genes with similar functions are likely to be regulated via the same mechanisms. It has been diff...
Dominic J. Allocco, Isaac S. Kohane, Atul J. Butte