The availability of entire genome sequences, coupled with genome-wide studies of gene expression, offers promise for discovering new pathways along with their regulatory programs....
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...
The development of structure-learning algorithms for gene regulatory networks depends heavily on the availability of synthetic data sets that contain both the original network and ...
Koenraad Van Leemput, Tim Van den Bulcke, Thomas D...
Recently, the concept of mutual information has been proposed for inferring the structure of genetic regulatory networks from gene expression profiling. After analyzing the limitat...
This paper addresses the inference of the transcriptional regulatory network of Bacillus subtilis. Two inference approaches, a linear, additive model and a non-linear power-law mo...
Anshuman Gupta, Jeffrey D. Varner, Costas D. Maran...