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» Extracting active pathways from gene expression data
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RECOMB
2009
Springer
15 years 11 months ago
Evaluating Between-Pathway Models with Expression Data
Abstract. Between-Pathway Models (BPMs) are network motifs consisting of pairs of putative redundant pathways. In this paper, we show how adding another source of high-throughput d...
Benjamin J. Hescott, Mark D. M. Leiserson, Lenore ...
BMCBI
2010
107views more  BMCBI 2010»
14 years 10 months ago
Detection of characteristic sub pathway network for angiogenesis based on the comprehensive pathway network
Background: Pathways in biological system often cooperate with each other to function. Changes of interactions among pathways tightly associate with alterations in the properties ...
Yezhou Huang, Shao Li
86
Voted
BMCBI
2010
130views more  BMCBI 2010»
14 years 10 months ago
Knowledge-guided gene ranking by coordinative component analysis
Background: In cancer, gene networks and pathways often exhibit dynamic behavior, particularly during the process of carcinogenesis. Thus, it is important to prioritize those gene...
Chen Wang, Jianhua Xuan, Huai Li, Yue Wang, Ming Z...
62
Voted
ISMB
2003
14 years 11 months ago
Discovering molecular pathways from protein interaction and gene expression data
Eran Segal, Haidong Wang, Daphne Koller
BMCBI
2004
151views more  BMCBI 2004»
14 years 10 months ago
A computational approach for ordering signal transduction pathway components from genomics and proteomics Data
Background: Signal transduction is one of the most important biological processes by which cells convert an external signal into a response. Novel computational approaches to mapp...
Yin Liu, Hongyu Zhao