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» Extracting and Explaining Biological Knowledge in Microarray...
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BMCBI
2010
170views more  BMCBI 2010»
14 years 9 months ago
Integrative analysis of gene expression and copy number alterations using canonical correlation analysis
Background: With the rapid development of new genetic measurement methods, several types of genetic alterations can be quantified in a high-throughput manner. While the initial fo...
Charlotte Soneson, Henrik Lilljebjörn, Thoas ...
NLDB
2005
Springer
15 years 3 months ago
Combining Biological Databases and Text Mining to Support New Bioinformatics Applications
Abstract. A large amount of biological knowledge today is only available from full-text research papers. Since neither manual database curators nor users can keep up with the rapid...
René Witte, Christopher J. O. Baker
BIODATAMINING
2008
130views more  BIODATAMINING 2008»
14 years 9 months ago
Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profil
Background: Contrary to the traditional biology approach, where the expression patterns of a handful of genes are studied at a time, microarray experiments enable biologists to st...
Qicheng Ma, Gung-Wei Chirn, Joseph D. Szustakowski...
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ISMB
1993
14 years 11 months ago
Prediction of Primate Splice Junction Gene Sequences with a Cooperative Knowledge Acquisition System
Wepropose a cooperative conceptual modelling environment in which two agents interact : the machineand the humanexpert. Theformer is able to extract knowledge from data using a sy...
Engelbert Mephu Nguifo, Jean Sallantin
BMCBI
2008
83views more  BMCBI 2008»
14 years 9 months ago
Integrative bioinformatics analysis of transcriptional regulatory programs in breast cancer cells
Background: Microarray technology has unveiled transcriptomic differences among tumors of various phenotypes, and, especially, brought great progress in molecular understanding of...
Atsushi Niida, Andrew D. Smith, Seiya Imoto, Shuic...