48 search results - page 1 / 10 » Extracting transcription factor binding sites from unaligned... |
76
Voted
BMCBI
2008
14 years 10 months ago
2008
Background: Transcription factor binding sites (TFBSs) are crucial in the regulation of gene transcription. Recently, chromatin immunoprecipitation followed by cDNA microarray hyb...
ISMB
2000
14 years 11 months ago
2000
Understanding the mechanismsthat determine the regulation of geneexpression is an important and challenging problem. A fundamental subproblem is to identify DNA-bindingsites for u...
BMCBI
2005
14 years 10 months ago
2005
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
89
Voted
BMCBI
2008
14 years 10 months ago
2008
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
88
Voted
BMCBI
2006
14 years 10 months ago
2006
Background: Identifying cis-regulatory elements is crucial to understanding gene expression, which highlights the importance of the computational detection of overrepresented tran...