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» Extraction of informative genes from microarray data
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125
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BMCBI
2010
115views more  BMCBI 2010»
15 years 3 months ago
Integration of multiple data sources to prioritize candidate genes using discounted rating system
Background: Identifying disease gene from a list of candidate genes is an important task in bioinformatics. The main strategy is to prioritize candidate genes based on their simil...
Yongjin Li, Jagdish Chandra Patra
RECOMB
2009
Springer
16 years 4 months ago
Evaluating Between-Pathway Models with Expression Data
Abstract. Between-Pathway Models (BPMs) are network motifs consisting of pairs of putative redundant pathways. In this paper, we show how adding another source of high-throughput d...
Benjamin J. Hescott, Mark D. M. Leiserson, Lenore ...
127
Voted
BMCBI
2007
135views more  BMCBI 2007»
15 years 3 months ago
Measuring similarities between gene expression profiles through new data transformations
Background: Clustering methods are widely used on gene expression data to categorize genes with similar expression profiles. Finding an appropriate (dis)similarity measure is crit...
Kyungpil Kim, Shibo Zhang, Keni Jiang, Li Cai, In-...
123
Voted
BMCBI
2005
93views more  BMCBI 2005»
15 years 3 months ago
Identification of novel prognostic markers in cervical intraepithelial neoplasia using LDMAS (LOH Data Management and Analysis S
Background: Detection of Loss of Heterozygosity (LOH) is one of the most common molecular applications in the study of human diseases, in particular cancer. The technique is commo...
Rifat A. Hamoudi, Amina El-Hamidi, Ming-Qing Du
146
Voted
BMCBI
2005
143views more  BMCBI 2005»
15 years 3 months ago
Evaluation of BioCreAtIvE assessment of task 2
Background: Molecular Biology accumulated substantial amounts of data concerning functions of genes and proteins. Information relating to functional descriptions is generally extr...
Christian Blaschke, Eduardo Andrés Le&oacut...