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» Extraction of informative genes from microarray data
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152
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WABI
2001
Springer
162views Bioinformatics» more  WABI 2001»
15 years 8 months ago
A Simple Hyper-Geometric Approach for Discovering Putative Transcription Factor Binding Sites
A central issue in molecular biology is understanding the regulatory mechanisms that control gene expression. The recent flood of genomic and postgenomic data opens the way for co...
Yoseph Barash, Gill Bejerano, Nir Friedman
114
Voted
SIBGRAPI
2006
IEEE
15 years 9 months ago
Extracting Discriminative Information from Medical Images: A Multivariate Linear Approach
Statistical discrimination methods are suitable not only for classification but also for characterisation of differences between a reference group of patterns and the population u...
Carlos E. Thomaz, Nelson A. O. Aguiar, Sergio H. A...
140
Voted
BMCBI
2008
127views more  BMCBI 2008»
15 years 3 months ago
Gene and pathway identification with Lp penalized Bayesian logistic regression
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
Zhenqiu Liu, Ronald B. Gartenhaus, Ming Tan, Feng ...
121
Voted
BMCBI
2010
102views more  BMCBI 2010»
15 years 3 months ago
Missing genes in the annotation of prokaryotic genomes
Background: Protein-coding gene detection in prokaryotic genomes is considered a much simpler problem than in intron-containing eukaryotic genomes. However there have been reports...
Andrew S. Warren, Jeremy S. Archuleta, Wu-chun Fen...
133
Voted
BMCBI
2007
146views more  BMCBI 2007»
15 years 3 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...