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» Extraction of informative genes from microarray data
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BMCBI
2008
142views more  BMCBI 2008»
13 years 6 months ago
Microarray data mining: A novel optimization-based approach to uncover biologically coherent structures
Background: DNA microarray technology allows for the measurement of genome-wide expression patterns. Within the resultant mass of data lies the problem of analyzing and presenting...
Meng Piao Tan, Erin N. Smith, James R. Broach, Chr...
BMCBI
2008
115views more  BMCBI 2008»
13 years 6 months ago
Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
Background: Time-course microarray experiments are being increasingly used to characterize dynamic biological processes. In these experiments, the goal is to identify genes differ...
Sudhakar Jonnalagadda, Rajagopalan Srinivasan
BMCBI
2008
135views more  BMCBI 2008»
13 years 6 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
BIBE
2005
IEEE
13 years 12 months ago
Selecting Informative Genes from Microarray Dataset by Incorporating Gene Ontology
Selecting informative genes from microarray experiments is one of the most important data analysis steps for deciphering biological information imbedded in such experiments. Howev...
Xian Xu, Aidong Zhang
COMPLIFE
2006
Springer
13 years 10 months ago
Relational Subgroup Discovery for Descriptive Analysis of Microarray Data
Abstract. This paper presents a method that uses gene ontologies, together with the paradigm of relational subgroup discovery, to help find description of groups of genes different...
Igor Trajkovski, Filip Zelezný, Jakub Tolar...