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» Extraction of informative genes from microarray data
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143
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BMCBI
2005
114views more  BMCBI 2005»
15 years 3 months ago
Quality determination and the repair of poor quality spots in array experiments
Background: A common feature of microarray experiments is the occurence of missing gene expression data. These missing values occur for a variety of reasons, in particular, becaus...
Brian D. M. Tom, Walter R. Gilks, Elizabeth T. Bro...
141
Voted
BMCBI
2010
160views more  BMCBI 2010»
15 years 3 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian
BMCBI
2006
106views more  BMCBI 2006»
15 years 3 months ago
Methodological study of affine transformations of gene expression data with proposed robust non-parametric multi-dimensional nor
Background: Low-level processing and normalization of microarray data are most important steps in microarray analysis, which have profound impact on downstream analysis. Multiple ...
Henrik Bengtsson, Ola Hössjer
AIME
2009
Springer
15 years 7 months ago
Effect of Background Correction on Cancer Classification with Gene Expression Data
This paper empirically compares six background correction methods aimed at removing unspecific background noise of the overall signal level measured by a scanner across microarrays...
Adelaide Freitas, Gladys Castillo, Ana São ...
124
Voted
BMCBI
2006
126views more  BMCBI 2006»
15 years 3 months ago
Differential prioritization between relevance and redundancy in correlation-based feature selection techniques for multiclass ge
Background: Due to the large number of genes in a typical microarray dataset, feature selection looks set to play an important role in reducing noise and computational cost in gen...
Chia Huey Ooi, Madhu Chetty, Shyh Wei Teng