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139
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BMCBI
2008
15 years 3 months ago
2008
Background: DNA methylation is an important epigenetic modification of the genome. Abnormal DNA methylation may result in silencing of tumor suppressor genes and is common in a va...
149
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BMCBI
2005
15 years 3 months ago
2005
Background: A critical step in processing oligonucleotide microarray data is combining the information in multiple probes to produce a single number that best captures the express...
129
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BMCBI
2005
2005
A microarray data-based semi-kinetic method for predicting quantitative dynamics of genetic networks
15 years 3 months ago
Background: Elucidating the dynamic behaviour of genetic regulatory networks is one of the most significant challenges in systems biology. However, conventional quantitative predi...
112
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BMCBI
2006
15 years 3 months ago
2006
Background: Aristolochic acid (AA) is the active component of herbal drugs derived from Aristolochia species that have been used for medicinal purposes since antiquity. AA, howeve...
125
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BMCBI
2006
15 years 3 months ago
2006
In this short article, we discuss a simple method for assessing sample size requirements in microarray experiments. Our method starts with the output from a permutation-based anal...