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BMCBI
2010
156views more  BMCBI 2010»
14 years 9 months ago
Global screening of potential Candida albicans biofilm-related transcription factors via network comparison
Background: Candida albicans is a commonly encountered fungal pathogen in humans. The formation of biofilm is a major virulence factor in C. albicans pathogenesis and is related t...
Yu-Chao Wang, Chung-Yu Lan, Wen-Ping Hsieh, Luis A...
BMCBI
2010
178views more  BMCBI 2010»
14 years 9 months ago
An improved method for scoring protein-protein interactions using semantic similarity within the Gene Ontology
Background: Semantic similarity measures are useful to assess the physiological relevance of protein-protein interactions (PPIs). They quantify similarity between proteins based o...
Shobhit Jain, Gary D. Bader
BMCBI
2007
120views more  BMCBI 2007»
14 years 9 months ago
Recognition of interferon-inducible sites, promoters, and enhancers
Background: Computational analysis of gene regulatory regions is important for prediction of functions of many uncharacterized genes. With this in mind, search of the target genes...
Elena A. Ananko, Yury V. Kondrakhin, Tatyana I. Me...
BMCBI
2008
122views more  BMCBI 2008»
14 years 9 months ago
Reconstructing networks of pathways via significance analysis of their intersections
Background: Significance analysis at single gene level may suffer from the limited number of samples and experimental noise that can severely limit the power of the chosen statist...
Mirko Francesconi, Daniel Remondini, Nicola Nerett...
BMCBI
2006
114views more  BMCBI 2006»
14 years 9 months ago
Epigenetic acquisition of inducibility of type III cytotoxicity in P. aeruginosa
Background: Pseudomonas aeruginosa, an opportunistic pathogen, is often encountered in chronic lung diseases such as cystic fibrosis or chronic obstructive pneumonia, as well as a...
Didier Filopon, Annabelle Mérieau, Gilles B...