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CCS
2009
ACM
15 years 4 months ago
Privacy-preserving genomic computation through program specialization
In this paper, we present a new approach to performing important classes of genomic computations (e.g., search for homologous genes) that makes a significant step towards privacy...
Rui Wang, XiaoFeng Wang, Zhou Li, Haixu Tang, Mich...
BMCBI
2005
115views more  BMCBI 2005»
14 years 9 months ago
MPrime: efficient large scale multiple primer and oligonucleotide design for customized gene microarrays
Background: Enhancements in sequencing technology have recently yielded assemblies of large genomes including rat, mouse, human, fruit fly, and zebrafish. The availability of larg...
Eric C. Rouchka, Abdelnaby Khalyfa, Nigel G. F. Co...
NAR
2011
256views Computer Vision» more  NAR 2011»
14 years 9 days ago
COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
COSMIC (http://www.sanger.ac.uk/cosmic) curates comprehensive information on somatic mutations in human cancer. Release v48 (July 2010) describes over 136 000 coding mutations in ...
Simon A. Forbes, Nidhi Bindal, Sally Bamford, Char...
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NAR
2007
149views more  NAR 2007»
14 years 9 months ago
UniHI: an entry gate to the human protein interactome
Systematic mapping of protein–protein interactions has become a central task of functional genomics. To map the human interactome, several strategies have recently been pursued....
Gautam Chaurasia, Yasir Iqbal, Christian Häni...
BMCBI
2008
130views more  BMCBI 2008»
14 years 9 months ago
Gene Prospector: An evidence gateway for evaluating potential susceptibility genes and interacting risk factors for human diseas
Background: Millions of single nucleotide polymorphisms have been identified as a result of the human genome project and the rapid advance of high throughput genotyping technology...
Wei Yu, Anja Wulf, Tiebin Liu, Muin J. Khoury, Mar...