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BMCBI
2006
117views more  BMCBI 2006»
13 years 6 months ago
SigFlux: A novel network feature to evaluate the importance of proteins in signal transduction networks
Background: Measuring each protein's importance in signaling networks helps to identify the crucial proteins in a cellular process, find the fragile portion of the biology sy...
Wei Liu, Dong Li, Jiyang Zhang, Yunping Zhu, Fuchu...
BMCBI
2006
113views more  BMCBI 2006»
13 years 6 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
BMCBI
2005
147views more  BMCBI 2005»
13 years 6 months ago
GATA: a graphic alignment tool for comparative sequence analysis
Background: Several problems exist with current methods used to align DNA sequences for comparative sequence analysis. Most dynamic programming algorithms assume that conserved se...
David A. Nix, Michael B. Eisen
BMCBI
2005
149views more  BMCBI 2005»
13 years 6 months ago
The PD-(D/E)XK superfamily revisited: identification of new members among proteins involved in DNA metabolism and functional pre
Background: The PD-(D/E)XK nuclease superfamily, initially identified in type II restriction endonucleases and later in many enzymes involved in DNA recombination and repair, is o...
Jan Kosinski, Marcin Feder, Janusz M. Bujnicki
ACMACE
2009
ACM
13 years 11 months ago
Familiars: representing Facebook users' social behaviour through a reflective playful experience
In this paper, we describe the design and development of a social game called Familiars. Inspired by the daemons in Pullman’s “Dark Material” trilogy, Familiars are animal c...
Ben Kirman, Eva Ferrari, Shaun Lawson, Jonathan Fr...