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121
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BMCBI
2006
108views more  BMCBI 2006»
15 years 3 months ago
An improved map of conserved regulatory sites for Saccharomyces cerevisiae
Background: The regulatory map of a genome consists of the binding sites for proteins that determine the transcription of nearby genes. An initial regulatory map for S. cerevisiae...
Kenzie D. MacIsaac, Ting Wang, D. Benjamin Gordon,...
135
Voted
BMCBI
2006
156views more  BMCBI 2006»
15 years 3 months ago
Detecting the limits of regulatory element conservation and divergence estimation using pairwise and multiple alignments
Background: Molecular evolutionary studies of noncoding sequences rely on multiple alignments. Yet how multiple alignment accuracy varies across sequence types, tree topologies, d...
Daniel A. Pollard, Alan M. Moses, Venky N. Iyer, M...
BMCBI
2011
14 years 10 months ago
The impact of quantitative optimization of hybridization conditions on gene expression analysis
Background: With the growing availability of entire genome sequences, an increasing number of scientists can exploit oligonucleotide microarrays for genome-scale expression studie...
Peter Sykacek, David P. Kreil, Lisa A. Meadows, Ri...
113
Voted
ICC
2009
IEEE
123views Communications» more  ICC 2009»
15 years 10 months ago
Combining Hidden Markov Models for Improved Anomaly Detection
—In host-based intrusion detection systems (HIDS), anomaly detection involves monitoring for significant deviations from normal system behavior. Hidden Markov Models (HMMs) have...
Wael Khreich, Eric Granger, Robert Sabourin, Ali M...
142
Voted
IPPS
2009
IEEE
15 years 10 months ago
Accelerating HMMer on FPGAs using systolic array based architecture
HMMer is a widely-used bioinformatics software package that uses profile HMMs (Hidden Markov Models) to model the primary structure consensus of a family of protein or nucleic aci...
Yanteng Sun, Peng Li, Guochang Gu, Yuan Wen, Yuan ...