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BMCBI
2006
124views more  BMCBI 2006»
14 years 9 months ago
Predicting transcription factor binding sites using local over-representation and comparative genomics
Background: Identifying cis-regulatory elements is crucial to understanding gene expression, which highlights the importance of the computational detection of overrepresented tran...
Matthieu Defrance, Hélène Touzet
69
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WSC
2004
14 years 11 months ago
An Efficient Screening Methodology for a Priori Assessed Non-Influential Factors
The choice of which factors to choose to vary in a simulation to effect a change in the measure of interest is difficult. Many factors are a priori judged not to effect the measur...
Thomas M. Cioppa
ISMB
2000
14 years 11 months ago
A Statistical Method for Finding Transcription Factor Binding Sites
Understanding the mechanismsthat determine the regulation of geneexpression is an important and challenging problem. A fundamental subproblem is to identify DNA-bindingsites for u...
Saurabh Sinha, Martin Tompa
TNN
2008
128views more  TNN 2008»
14 years 9 months ago
Nonnegative Matrix Factorization in Polynomial Feature Space
Abstract--Plenty of methods have been proposed in order to discover latent variables (features) in data sets. Such approaches include the principal component analysis (PCA), indepe...
Ioan Buciu, Nikos Nikolaidis, Ioannis Pitas
AMC
2010
143views more  AMC 2010»
14 years 9 months ago
Fixed-point iterations in determining a Tikhonov regularization parameter in Kirsch's factorization method
Kirsch's factorization method is a fast inversion technique for visualizing the profile of a scatterer from measurements of the far-field pattern. The mathematical basis of t...
Koung Hee Leem, George Pelekanos, Fermín S....