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ESWA
2007
100views more  ESWA 2007»
14 years 9 months ago
Using memetic algorithms with guided local search to solve assembly sequence planning
The goal of assembly planning consists in generating feasible sequences to assemble a product and selecting an efficient assembly sequence from which related constraint factors su...
Hwai-En Tseng, Wen-Pai Wang, Hsun-Yi Shih
BMCBI
2006
87views more  BMCBI 2006»
14 years 10 months ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen
BMCBI
2008
121views more  BMCBI 2008»
14 years 10 months ago
BioSAVE: Display of scored annotation within a sequence context
Background: Visualization of sequence annotation is a common feature in many bioinformatics tools. For many applications it is desirable to restrict the display of such annotation...
Richard F. Pollock, Boris Adryan
BMCBI
2006
98views more  BMCBI 2006»
14 years 10 months ago
Scanning sequences after Gibbs sampling to find multiple occurrences of functional elements
Background: Many DNA regulatory elements occur as multiple instances within a target promoter. Gibbs sampling programs for finding DNA regulatory elements de novo can be prohibiti...
Kannan Tharakaraman, Leonardo Mariño-Ram&ia...
BMCBI
2008
105views more  BMCBI 2008»
14 years 10 months ago
Novel computational methods for increasing PCR primer design effectiveness in directed sequencing
Background: Polymerase chain reaction (PCR) is used in directed sequencing for the discovery of novel polymorphisms. As the first step in PCR directed sequencing, effective PCR pr...
Kelvin Li, Anushka Brownley, Timothy B. Stockwell,...