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» Family pairwise search with embedded motif models
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GCB
2009
Springer
105views Biometrics» more  GCB 2009»
15 years 4 months ago
Maximum Likelihood Estimation of Weight Matrices for Targeted Homology Search
: Genome annotation relies to a large extent on the recognition of homologs to already known genes. The starting point for such protocols is a collection of known sequences from on...
Peter Menzel, Jan Gorodkin, Peter F. Stadler
CCECE
2006
IEEE
15 years 3 months ago
Evaluation of RNA Secondary Structure Motifs using Regression Analysis
Recent experimental evidences have shown that ribonucleic acid (RNA) plays a greater role in the cell than previously thought. An ensemble of RNA sequences believed to contain sig...
Mohammad Anwar, Marcel Turcotte
NIPS
2004
14 years 10 months ago
Euclidean Embedding of Co-Occurrence Data
Embedding algorithms search for low dimensional structure in complex data, but most algorithms only handle objects of a single type for which pairwise distances are specified. Thi...
Amir Globerson, Gal Chechik, Fernando C. Pereira, ...
BMCBI
2002
133views more  BMCBI 2002»
14 years 9 months ago
Identification and characterization of subfamily-specific signatures in a large protein superfamily by a hidden Markov model app
Background: Most profile and motif databases strive to classify protein sequences into a broad spectrum of protein families. The next step of such database studies should include ...
Kevin Truong, Mitsuhiko Ikura
BMCBI
2011
14 years 29 days ago
GPCR-SSFE: A comprehensive database of G-protein-coupled receptor template predictions and homology models
Background: G protein-coupled receptors (GPCRs) transduce a wide variety of extracellular signals to within the cell and therefore have a key role in regulating cell activity and ...
Catherine L. Worth, Annika Kreuchwig, Gunnar Klein...