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ISMB
1994
14 years 11 months ago
GeneQuiz: A Workbench for Sequence Analysis
Wepresent the prototype of a software system, cMledGeneQuiz,for large-scale biological sequence analysis. The system was designed to meet the needs that arise in computational seq...
Michael Scharf, Reinhard Schneider, Georg Casari, ...
ATAL
2010
Springer
14 years 11 months ago
Combining manual feedback with subsequent MDP reward signals for reinforcement learning
As learning agents move from research labs to the real world, it is increasingly important that human users, including those without programming skills, be able to teach agents de...
W. Bradley Knox, Peter Stone
BMCBI
2010
139views more  BMCBI 2010»
14 years 10 months ago
A highly efficient multi-core algorithm for clustering extremely large datasets
Background: In recent years, the demand for computational power in computational biology has increased due to rapidly growing data sets from microarray and other high-throughput t...
Johann M. Kraus, Hans A. Kestler
BMCBI
2007
130views more  BMCBI 2007»
14 years 10 months ago
HMM-ModE - Improved classification using profile hidden Markov models by optimising the discrimination threshold and modifying e
Background: Profile Hidden Markov Models (HMM) are statistical representations of protein families derived from patterns of sequence conservation in multiple alignments and have b...
Prashant K. Srivastava, Dhwani K. Desai, Soumyadee...
BMCBI
2008
138views more  BMCBI 2008»
14 years 10 months ago
Inference of haplotypic phase and missing genotypes in polyploid organisms and variable copy number genomic regions
Background: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organ...
Shu-Yi Su, Jonathan White, David J. Balding, Lachl...