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BMCBI
2008
117views more  BMCBI 2008»
14 years 9 months ago
New resampling method for evaluating stability of clusters
Background: Hierarchical clustering is a widely applied tool in the analysis of microarray gene expression data. The assessment of cluster stability is a major challenge in cluste...
Irina Gana Dresen, Tanja Boes, Johannes Hüsin...
BMCBI
2010
139views more  BMCBI 2010»
14 years 9 months ago
A highly efficient multi-core algorithm for clustering extremely large datasets
Background: In recent years, the demand for computational power in computational biology has increased due to rapidly growing data sets from microarray and other high-throughput t...
Johann M. Kraus, Hans A. Kestler
DILS
2004
Springer
15 years 2 months ago
Heterogeneous Data Integration with the Consensus Clustering Formalism
Meaningfully integrating massive multi-experimental genomic data sets is becoming critical for the understanding of gene function. We have recently proposed methodologies for integ...
Vladimir Filkov, Steven Skiena
BMCBI
2008
202views more  BMCBI 2008»
14 years 9 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2008
200views more  BMCBI 2008»
14 years 9 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia