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102
Voted
BMCBI
2010
156views more  BMCBI 2010»
15 years 3 months ago
Estimating the individualized HIV-1 genetic barrier to resistance using a nelfinavir fitness landscape
Background: Failure on Highly Active Anti-Retroviral Treatment is often accompanied with development of antiviral resistance to one or more drugs included in the treatment. In gen...
Kristof Theys, Koen Deforche, Gertjan Beheydt, Yve...
132
Voted
BMCBI
2010
152views more  BMCBI 2010»
15 years 3 months ago
FITBAR: a web tool for the robust prediction of prokaryotic regulons
Background: The binding of regulatory proteins to their specific DNA targets determines the accurate expression of the neighboring genes. The in silico prediction of new binding s...
Jacques Oberto
BMCBI
2008
111views more  BMCBI 2008»
15 years 3 months ago
Probabilistic base calling of Solexa sequencing data
Background: Solexa/Illumina short-read ultra-high throughput DNA sequencing technology produces millions of short tags (up to 36 bases) by parallel sequencing-by-synthesis of DNA ...
Jacques Rougemont, Arnaud Amzallag, Christian Isel...
116
Voted
BMCBI
2006
137views more  BMCBI 2006»
15 years 3 months ago
Genome BLAST distance phylogenies inferred from whole plastid and whole mitochondrion genome sequences
Background: Phylogenetic methods which do not rely on multiple sequence alignments are important tools in inferring trees directly from completely sequenced genomes. Here, we exte...
Alexander F. Auch, Stefan R. Henz, Barbara R. Holl...
JNW
2008
173views more  JNW 2008»
15 years 3 months ago
Dominating Set Theory based Semantic Overlay Networks for Efficient and Resilient Content Distribution
Recently overlay networks have emerged as an efficient and flexible method for content distribution. An overlay network is a network running on top of another network, usually the ...
J. Amutharaj, S. Radhakrishnan