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ICDE
2010
IEEE
199views Database» more  ICDE 2010»
15 years 6 months ago
Mining mutation chains in biological sequences
— The increasing infectious disease outbreaks has led to a need for new research to better understand the disease’s origins, epidemiological features and pathogenicity caused b...
Chang Sheng, Wynne Hsu, Mong-Li Lee, Joo Chuan Ton...
71
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RECOMB
2006
Springer
16 years 2 days ago
A New Approach to Protein Identification
Advances in tandem mass-spectrometry (MS/MS) steadily increase the rate of generation of MS/MS spectra and make it more computationally challenging to analyze such huge datasets. A...
Nuno Bandeira, Dekel Tsur, Ari Frank, Pavel A. Pev...
BMCBI
2008
123views more  BMCBI 2008»
14 years 12 months ago
Shape based indexing for faster search of RNA family databases
Background: Most non-coding RNA families exert their function by means of a conserved, common secondary structure. The Rfam data base contains more than five hundred structurally ...
Stefan Janssen, Jens Reeder, Robert Giegerich
BMCBI
2011
14 years 6 months ago
Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
Stefan Wolfsheimer, Inke Herms, Sven Rahmann, Alex...
BMCBI
2008
122views more  BMCBI 2008»
14 years 12 months ago
ESLpred2: improved method for predicting subcellular localization of eukaryotic proteins
Background: The expansion of raw protein sequence databases in the post genomic era and availability of fresh annotated sequences for major localizations particularly motivated us...
Aarti Garg, Gajendra P. S. Raghava