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BMCBI
2007
233views more  BMCBI 2007»
14 years 11 months ago
160-fold acceleration of the Smith-Waterman algorithm using a field programmable gate array (FPGA)
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
Isaac T. S. Li, Warren Shum, Kevin Truong
BMCBI
2006
117views more  BMCBI 2006»
14 years 11 months ago
Gene Designer: a synthetic biology tool for constructing artificial DNA segments
Background: Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization, RNAi re...
Alan Villalobos, Jon E. Ness, Claes Gustafsson, Je...
NAR
2002
82views more  NAR 2002»
14 years 11 months ago
PALS db: Putative Alternative Splicing database
PALS db is a collection of Putative Alternative Splicing information from 19 936 human UniGene clusters and 16 615 mouse UniGene clusters. Alternative splicing (AS) sites were pre...
Y.-H. Huang, Y.-T. Chen, J.-J. Lai, S.-T. Yang, U....
BMCBI
2006
102views more  BMCBI 2006»
14 years 11 months ago
MycoperonDB: a database of computationally identified operons and transcriptional units in Mycobacteria
Background: A key post genomics challenge is to identify how genes in an organism come together and perform physiological functions. An important first step in this direction is t...
Sarita Ranjan, Ranjit Kumar Gundu, Akash Ranjan
IEEECGIV
2006
IEEE
15 years 5 months ago
PathBank: Web-Based Querying and Visualziation of an Integrated Biological Pathway Database
PathBank is a web-based query and visualization system for biological pathways using an integrated pathway database. To address the needs for biologists to visualize and analyze b...
Joshua Wing Kei Ho, Tristan Manwaring, Seok-Hee Ho...