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» Fast and Accurate Alignment of Multiple Protein Networks
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ICASSP
2011
IEEE
14 years 3 months ago
Fast network querying algorithm for searching large-scale biological networks
Network querying aims to search a large network for subnetwork regions that are similar to a given query network. In this paper, we propose a novel algorithm for querying large sc...
Sayed Mohammad Ebrahim Sahraeian, Byung-Jun Yoon
CP
2003
Springer
15 years 4 months ago
A SAT-Based Approach to Multiple Sequence Alignment
Multiple sequence alignment is a central problem in Bioinformatics. A known integer programming approach is to apply branch-and-cut to exponentially large graph-theoretic models. T...
Steven David Prestwich, Desmond G. Higgins, Orla O...
BMCBI
2007
101views more  BMCBI 2007»
14 years 11 months ago
Relationship between insertion/deletion (indel) frequency of proteins and essentiality
Background: In a previous study, we demonstrated that some essential proteins from pathogenic organisms contained sizable insertions/deletions (indels) when aligned to human prote...
Simon K. Chan, Michael Hsing, Fereydoun Hormozdiar...
CIKM
2008
Springer
15 years 1 months ago
Pairwise statistical significance of local sequence alignment using multiple parameter sets
Background: Accurate estimation of statistical significance of a pairwise alignment is an important problem in sequence comparison. Recently, a comparative study of pairwise stati...
Ankit Agrawal, Xiaoqiu Huang
NAR
2006
164views more  NAR 2006»
14 years 11 months ago
FISH - family identification of sequence homologues using structure anchored hidden Markov models
The FISH server is highly accurate in identifying the family membership of domains in a query protein sequence, even in the case of very low sequence identities to known homologue...
Jeanette Tångrot, Lixiao Wang, Bo Kågs...