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BMCBI
2008
102views more  BMCBI 2008»
14 years 11 months ago
Fast splice site detection using information content and feature reduction
Background: Accurate identification of splice sites in DNA sequences plays a key role in the prediction of gene structure in eukaryotes. Already many computational methods have be...
A. K. M. A. Baten, Saman K. Halgamuge, Bill C. H. ...
AI
2006
Springer
14 years 11 months ago
Backward-chaining evolutionary algorithms
Starting from some simple observations on a popular selection method in Evolutionary Algorithms (EAs)--tournament selection--we highlight a previously-unknown source of inefficien...
Riccardo Poli, William B. Langdon
BMCBI
2006
179views more  BMCBI 2006»
14 years 11 months ago
Multiscale Hy3S: Hybrid stochastic simulation for supercomputers
Background: Stochastic simulation has become a useful tool to both study natural biological systems and design new synthetic ones. By capturing the intrinsic molecular fluctuation...
Howard Salis, Vassilios Sotiropoulos, Yiannis N. K...
BMCBI
2006
158views more  BMCBI 2006»
14 years 11 months ago
Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...
BMCBI
2006
115views more  BMCBI 2006»
14 years 11 months ago
The accuracy of several multiple sequence alignment programs for proteins
Background: There have been many algorithms and software programs implemented for the inference of multiple sequence alignments of protein and DNA sequences. The "true" ...
Paulo A. S. Nuin, Zhouzhi Wang, Elisabeth R. M. Ti...