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» Feature Engineering for a Gene Regulation Prediction Task
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BMCBI
2008
86views more  BMCBI 2008»
14 years 10 months ago
Predicting protein linkages in bacteria: Which method is best depends on task
Background: Applications of computational methods for predicting protein functional linkages are increasing. In recent years, several bacteria-specific methods for predicting link...
Anis Karimpour-Fard, Sonia M. Leach, Ryan T. Gill,...
BMCBI
2008
138views more  BMCBI 2008»
14 years 10 months ago
M-BISON: Microarray-based integration of data sources using networks
Background: The accurate detection of differentially expressed (DE) genes has become a central task in microarray analysis. Unfortunately, the noise level and experimental variabi...
Bernie J. Daigle Jr., Russ B. Altman
BMCBI
2005
114views more  BMCBI 2005»
14 years 9 months ago
Systematic analysis of human kinase genes: a large number of genes and alternative splicing events result in functional and stru
Background: Protein kinases are a well defined family of proteins, characterized by the presence of a common kinase catalytic domain and playing a significant role in many importa...
Luciano Milanesi, Mauro Petrillo, Leandra Sepe, An...
BMCBI
2006
127views more  BMCBI 2006»
14 years 10 months ago
Using local gene expression similarities to discover regulatory binding site modules
Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...
BMCBI
2010
131views more  BMCBI 2010»
14 years 7 months ago
A two-step site and mRNA-level model for predicting microRNA targets
Background: Despite experiments showing that the number of microRNA (miRNA) target sites is critical for miRNA targeting, most existing methods focus on identifying individual miR...
Takaya Saito, Pål Sætrom