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BIOCOMP
2006
15 years 1 months ago
Computational Inference of Compound-induced Anti-inflammatory Effects Across Time in an Adjuvant-induced Arthritis Rat Model
A number of diseases, such as arthritis and cardiovascular disorders impacting the lives of many people have strong inflammatory components. To elucidate the antiinflammatory mecha...
Jing Yu, Gabriel Helmlinger, Muriel Saulnier, Anna...
BMCBI
2008
130views more  BMCBI 2008»
14 years 12 months ago
Function approximation approach to the inference of reduced NGnet models of genetic networks
Background: The inference of a genetic network is a problem in which mutual interactions among genes are deduced using time-series of gene expression patterns. While a number of m...
Shuhei Kimura, Katsuki Sonoda, Soichiro Yamane, Hi...
BMCBI
2010
112views more  BMCBI 2010»
14 years 12 months ago
PhenoFam-gene set enrichment analysis through protein structural information
Background: With the current technological advances in high-throughput biology, the necessity to develop tools that help to analyse the massive amount of data being generated is e...
Maciej Paszkowski-Rogacz, Mikolaj Slabicki, M. Ter...
CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
15 years 5 months ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
GCB
2003
Springer
105views Biometrics» more  GCB 2003»
15 years 5 months ago
In silico prediction of UTR repeats using clustered EST data
Clustering of EST data is a method for the non-redundant representation of an organisms transcriptome. During clustering of large amounts of EST data, usually some large clusters ...
Stefan A. Rensing, Daniel Lang, Ralf Reski