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BMCBI
2007
113views more  BMCBI 2007»
14 years 12 months ago
CoryneRegNet 4.0 - A reference database for corynebacterial gene regulatory networks
Background: Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of micr...
Jan Baumbach
BMCBI
2007
123views more  BMCBI 2007»
14 years 12 months ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
ICDM
2008
IEEE
193views Data Mining» more  ICDM 2008»
15 years 6 months ago
Multiplicative Mixture Models for Overlapping Clustering
The problem of overlapping clustering, where a point is allowed to belong to multiple clusters, is becoming increasingly important in a variety of applications. In this paper, we ...
Qiang Fu, Arindam Banerjee
BMCBI
2007
239views more  BMCBI 2007»
14 years 12 months ago
Pre-processing Agilent microarray data
Background: Pre-processing methods for two-sample long oligonucleotide arrays, specifically the Agilent technology, have not been extensively studied. The goal of this study is to...
Marianna Zahurak, Giovanni Parmigiani, Wayne Yu, R...
BMCBI
2008
135views more  BMCBI 2008»
14 years 12 months ago
Identification of a small optimal subset of CpG sites as bio-markers from high-throughput DNA methylation profiles
Background: DNA methylation patterns have been shown to significantly correlate with different tissue types and disease states. High-throughput methylation arrays enable large-sca...
Hailong Meng, Edward Lenn Murrelle, Guoya Li