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GECCO
2005
Springer
146views Optimization» more  GECCO 2005»
15 years 5 months ago
An empirical study of the robustness of two module clustering fitness functions
Two of the attractions of search-based software engineering (SBSE) derive from the nature of the fitness functions used to guide the search. These have proved to be highly robust...
Mark Harman, Stephen Swift, Kiarash Mahdavi
NAR
2011
256views Computer Vision» more  NAR 2011»
14 years 2 months ago
COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
COSMIC (http://www.sanger.ac.uk/cosmic) curates comprehensive information on somatic mutations in human cancer. Release v48 (July 2010) describes over 136 000 coding mutations in ...
Simon A. Forbes, Nidhi Bindal, Sally Bamford, Char...
BMCBI
2005
201views more  BMCBI 2005»
14 years 11 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
BMCBI
2011
14 years 6 months ago
Sequential Interim Analyses of Survival Data in DNA Microarray Experiments
Background: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Freq...
Andreas Leha, Tim Beißbarth, Klaus Jung
NAR
2011
188views Computer Vision» more  NAR 2011»
14 years 2 months ago
NCBI Epigenomics: a new public resource for exploring epigenomic data sets
The Epigenomics database at the National Center for Biotechnology Information (NCBI) is a new resource that has been created to serve as a comprehensive public resource for whole-...
Ian M. Fingerman, Lee McDaniel, Xuan Zhang, Walter...