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BMCBI
2008
130views more  BMCBI 2008»
13 years 6 months ago
Function approximation approach to the inference of reduced NGnet models of genetic networks
Background: The inference of a genetic network is a problem in which mutual interactions among genes are deduced using time-series of gene expression patterns. While a number of m...
Shuhei Kimura, Katsuki Sonoda, Soichiro Yamane, Hi...
BMCBI
2006
94views more  BMCBI 2006»
13 years 6 months ago
Noise-injected neural networks show promise for use on small-sample expression data
Background: Overfitting the data is a salient issue for classifier design in small-sample settings. This is why selecting a classifier from a constrained family of classifiers, on...
Jianping Hua, James Lowey, Zixiang Xiong, Edward R...
BMCBI
2010
195views more  BMCBI 2010»
13 years 1 months ago
MBAT: A scalable informatics system for unifying digital atlasing workflows
Background: Digital atlases provide a common semantic and spatial coordinate system that can be leveraged to compare, contrast, and correlate data from disparate sources. As the q...
Daren Lee, Seth Ruffins, Queenie Ng, Nikhil Sane, ...
BMCBI
2008
153views more  BMCBI 2008»
13 years 6 months ago
GAPscreener: An automatic tool for screening human genetic association literature in PubMed using the support vector machine tec
Background: Synthesis of data from published human genetic association studies is a critical step in the translation of human genome discoveries into health applications. Although...
Wei Yu, Melinda Clyne, Siobhan M. Dolan, Ajay Yesu...
BMCBI
2010
113views more  BMCBI 2010»
13 years 6 months ago
Improving performance of mammalian microRNA target prediction
Background: MicroRNAs (miRNAs) are single-stranded non-coding RNAs known to regulate a wide range of cellular processes by silencing the gene expression at the protein and/or mRNA...
Hui Liu, Dong Yue, Yidong Chen, Shou-Jiang Gao, Yu...