Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Large-margin structured estimation methods minimize a convex upper bound of loss functions. While they allow for efficient optimization algorithms, these convex formulations are n...
Olivier Chapelle, Chuong B. Do, Quoc V. Le, Alexan...
Multiple sequence alignment represents a class of powerful bioinformatics tools with many uses in computational biology ranging from discovery of characteristic motifs and conserv...
TarO (http://www.compbio.dundee.ac.uk/taro) offers a single point of reference for key bioinformatics analyses relevant to selecting proteins or domains for study by structural bi...
Ian M. Overton, C. A. Johannes van Niekerk, Lester...
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...