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» Finding Gapped Motifs by a Novel Evolutionary Algorithm
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BMCBI
2005
125views more  BMCBI 2005»
14 years 9 months ago
DIALIGN-T: An improved algorithm for segment-based multiple sequence alignment
Background: We present a complete re-implementation of the segment-based approach to multiple protein alignment that contains a number of improvements compared to the previous ver...
Amarendran R. Subramanian, Jan Weyer-Menkhoff, Mic...
BMCBI
2011
14 years 4 months ago
A discriminative method for family-based protein remote homology detection that combines inductive logic programming and proposi
Background: Remote homology detection is a hard computational problem. Most approaches have trained computational models by using either full protein sequences or multiple sequenc...
Juliana S. Bernardes, Alessandra Carbone, Gerson Z...
GECCO
2011
Springer
264views Optimization» more  GECCO 2011»
14 years 28 days ago
Critical factors in the performance of novelty search
Novelty search is a recently proposed method for evolutionary computation designed to avoid the problem of deception, in which the fitness function guides the search process away...
Steijn Kistemaker, Shimon Whiteson
RECOMB
2004
Springer
15 years 9 months ago
Mining protein family specific residue packing patterns from protein structure graphs
Finding recurring residue packing patterns, or spatial motifs, that characterize protein structural families is an important problem in bioinformatics. To this end, we apply a nov...
Jun Huan, Wei Wang 0010, Deepak Bandyopadhyay, Jac...
GECCO
2004
Springer
137views Optimization» more  GECCO 2004»
15 years 2 months ago
Evolving Better Multiple Sequence Alignments
Aligning multiple DNA or protein sequences is a fundamental step in the analyses of phylogeny, homology and molecular structure. Heuristic algorithms are applied because optimal mu...
Luke Sheneman, James A. Foster