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BIOINFORMATICS
2005
152views more  BIOINFORMATICS 2005»
14 years 9 months ago
Intervention in context-sensitive probabilistic Boolean networks
Motivation: Intervention in a gene regulatory network is used to help it avoid undesirable states, such as those associated with a disease. Several types of intervention have been...
Ranadip Pal, Aniruddha Datta, Michael L. Bittner, ...
BMCBI
2005
84views more  BMCBI 2005»
14 years 9 months ago
A method of precise mRNA/DNA homology-based gene structure prediction
Background: Accurate and automatic gene finding and structural prediction is a common problem in bioinformatics, and applications need to be capable of handling non-canonical spli...
Alexander G. Churbanov, Mark Pauley, Daniel Quest,...
BMCBI
2005
93views more  BMCBI 2005»
14 years 9 months ago
Identification of novel prognostic markers in cervical intraepithelial neoplasia using LDMAS (LOH Data Management and Analysis S
Background: Detection of Loss of Heterozygosity (LOH) is one of the most common molecular applications in the study of human diseases, in particular cancer. The technique is commo...
Rifat A. Hamoudi, Amina El-Hamidi, Ming-Qing Du
BMCBI
2005
124views more  BMCBI 2005»
14 years 9 months ago
Probabilistic annotation of protein sequences based on functional classifications
: One of the most evident achievements of bioinformatics is the development of methods that transfer biological knowledge from characterised proteins to uncharacterised sequences. ...
Emmanuel D. Levy, Christos A. Ouzounis, Walter R. ...
BMCBI
2005
151views more  BMCBI 2005»
14 years 9 months ago
stam - a Bioconductor compliant R package for structured analysis of microarray data
Background: Genome wide microarray studies have the potential to unveil novel disease entities. Clinically homogeneous groups of patients can have diverse gene expression profiles...
Claudio Lottaz, Rainer Spang