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» Finding sRNA generative locales from high-throughput sequenc...
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BMCBI
2010
144views more  BMCBI 2010»
14 years 9 months ago
Finding sRNA generative locales from high-throughput sequencing data with NiBLS
Background: Next-generation sequencing technologies allow researchers to obtain millions of sequence reads in a single experiment. One important use of the technology is the seque...
Daniel MacLean, Vincent Moulton, David J. Studholm...
BMCBI
2010
133views more  BMCBI 2010»
14 years 7 months ago
Initial steps towards a production platform for DNA sequence analysis on the grid
Background: Bioinformatics is confronted with a new data explosion due to the availability of high throughput DNA sequencers. Data storage and analysis becomes a problem on local ...
Angela C. M. Luyf, Barbera D. C. van Schaik, Miche...
PREMI
2005
Springer
15 years 3 months ago
Computational Molecular Biology of Genome Expression and Regulation
Abstract. Technological advances in experimental and computational molecular biology have revolutionized the whole fields of biology and medicine. Large-scale sequencing, expressio...
Michael Q. Zhang
BMCBI
2006
133views more  BMCBI 2006»
14 years 9 months ago
Choosing negative examples for the prediction of protein-protein interactions
The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
Asa Ben-Hur, William Stafford Noble
BMCBI
2006
137views more  BMCBI 2006»
14 years 9 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan