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RECOMB
2007
Springer
16 years 5 days ago
Pairwise Global Alignment of Protein Interaction Networks by Matching Neighborhood Topology
We describe an algorithm, IsoRank, for global alignment of two protein-protein interaction (PPI) networks. IsoRank aims to maximize the overall match between the two networks; in c...
Rohit Singh, Jinbo Xu, Bonnie Berger
RECOMB
2004
Springer
16 years 5 days ago
The evolutionary capacity of protein structures
In nature, one finds large collections of different protein sequences exhibiting roughly the same three-dimensional structure, and this observation underpins the study of structur...
Leonid Meyerguz, David Kempe, Jon M. Kleinberg, Ro...
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STOC
2007
ACM
111views Algorithms» more  STOC 2007»
16 years 5 days ago
Low-end uniform hardness vs. randomness tradeoffs for AM
In 1998, Impagliazzo and Wigderson [IW98] proved a hardness vs. randomness tradeoff for BPP in the uniform setting, which was subsequently extended to give optimal tradeoffs for t...
Ronen Shaltiel, Christopher Umans
STOC
2006
ACM
138views Algorithms» more  STOC 2006»
16 years 5 days ago
The PCP theorem by gap amplification
The PCP theorem [3, 2] says that every language in NP has a witness format that can be checked probabilistically by reading only a constant number of bits from the proof. The cele...
Irit Dinur
STOC
2004
ACM
157views Algorithms» more  STOC 2004»
16 years 5 days ago
Derandomizing homomorphism testing in general groups
The main result of this paper is a near-optimal derandomization of the affine homomorphism test of Blum, Luby and Rubinfeld (Journal of Computer and System Sciences, 1993). We sho...
Amir Shpilka, Avi Wigderson
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